BDBM374329 (S)-(6-(6-(6-(1-aminoethyl)pyridin-2-yl)-4-(2-methoxyethoxy)-1H-indazol-1-yl)pyrazin-2-yl)methanol::US10246456, Example 481::US10577367, Example 481

SMILES COCCOc1cc(cc2n(ncc12)-c1cncc(CO)n1)-c1cccc(n1)[C@H](C)N

InChI Key InChIKey=IHSHOSKSURDYHY-AWEZNQCLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 374329   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374329((S)-(6-(6-(6-(1-aminoethyl)pyridin-2-yl)-4-(2-meth...)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374329((S)-(6-(6-(6-(1-aminoethyl)pyridin-2-yl)-4-(2-meth...)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM374329((S)-(6-(6-(6-(1-aminoethyl)pyridin-2-yl)-4-(2-meth...)
Affinity DataIC50: <100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent