BDBM376368 N-(3-(methyl- carbamoyl) benzyl)-6H- isochromeno [3,4-c]pyridine-8- carboxamide::US9914740, VII-6
SMILES CNC(=O)c1cccc(CNC(=O)c2ccc-3c(COc4cnccc-34)c2)c1
InChI Key InChIKey=UYQVTFFVWVLMAA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 376368
Affinity DataIC50: 1.34nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of ROCK1 (unknown origin) using FITC-AHA-AKRRRLSSLRA-OH as substrate by caliper assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using FITC-AHA-AKRRRLSSLRA-OH as substrate by caliper assayMore data for this Ligand-Target Pair