BDBM376369 (S)-N-(3-((1- ethylpyrrolidin- 2-yl)methyl- carbamoyl)benzyl)- 6H-ischromeno [3,4-c]pyridine- 8-carboxamide::US9914740, VII-7

SMILES CCN1CCC[C@H]1NC(=O)c1cccc(CNC(=O)c2ccc-3c(COc4cnccc-34)c2)c1

InChI Key InChIKey=IUWJJQNFKNWIDS-VWLOTQADSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376369   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376369((S)-N-(3-((1- ethylpyrrolidin- 2-yl)methyl- carbam...)
Affinity DataIC50:  1.5nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent