BDBM376370 US9914740, VII-8::methyl 5-((6H- isochromeno [3,4-c]pyridine-8- carboxamido) methyl)-2- fluorobenzoate

SMILES COC(=O)c1cc(CNC(=O)c2ccc-3c(COc4cnccc-34)c2)ccc1F

InChI Key InChIKey=CFYIFASHJDLQJS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376370   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376370(US9914740, VII-8 | methyl 5-((6H- isochromeno [3,4...)
Affinity DataIC50:  2.54nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent