BDBM376378 US9914740, VIII-4::methyl 3-((6-methyl-6H- isochromeno[3,4-c]pyridine- 8-carboxamido)methyl) benzoate

SMILES COC(=O)c1cccc(CNCc2ccc-3c(c2)C(C)Oc2cnccc-32)c1

InChI Key InChIKey=OBWMJELPIWEEES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376378   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376378(US9914740, VIII-4 | methyl 3-((6-methyl-6H- isochr...)
Affinity DataIC50:  0.340nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent