BDBM377781 (R)-5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-(2-fluorobenzyl)phenyl)-1H-pyrazole-4-carboxamide::US10266513, Example 75

SMILES NC(=O)c1c(N)n(nc1-c1ccc(Cc2ccccc2F)cc1)[C@@H]1CCCN(C1)C#N

InChI Key InChIKey=AUYWEKDSPKNPKL-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377781   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM377781((R)-5-amino-1-(1-cyanopiperidin-3-yl)-3-(4-(2-fluo...)
Affinity DataIC50:  0.810nMAssay Description:TR-FRET LanthaScreen assays were performed by incubating a dilution series of inhibitor concentrations with 50 μM ATP, 100 nM FAM-Srctide peptid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent