BDBM378698 N-(1-{1-[4-(benzyloxy)phenyl]ethyl}azetidin-3-yl)-5-cyclopropylpyridazine-3-carboxamide::US10266526, Compound 836

SMILES CC(N1CC(C1)NC(=O)c1cc(cnn1)C1CC1)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=NBJNKEHREQNUCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378698   

TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM378698(N-(1-{1-[4-(benzyloxy)phenyl]ethyl}azetidin-3-yl)-...)
Affinity DataIC50:  26.5nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent