BDBM378844 US10266528, Compound 21

SMILES CC1(C)Cc2cc3C(=O)N(CCn3c2C1)c1cc(F)cc(c1CO)-c1ccnc2[nH]c(=O)[nH]c12

InChI Key InChIKey=BLEYSPWACQVODY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378844   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM378844(US10266528, Compound 21)
Affinity DataIC50: <10nMAssay Description:Briefly, 2.5× stocks of full-length human BTK (08-080) from CarnaBio USA, Inc., Natick, Mass., 1.6×ATP and appropriate kinKDR peptide substrate (FITC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent