BDBM380129 8-chloro-N-[4-(4-oxo- 3,4-dihydrophthalazin-1- yl)phenyl]imidazo[1,2- a]pyrazine-2- carboxamide::US9926282, Example 124
SMILES Clc1nccn2cc(nc12)C(=O)Nc1ccc(cc1)-c1n[nH]c(=O)c2ccccc12
InChI Key InChIKey=ZQKPJHWAVNURCG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 380129
Affinity DataIC50: <100nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair