BDBM38105 US10093646, Example 20::US10774065, Example 20::US11401259, Example 20

SMILES Nc1nc(cnc1-c1cccc(Cl)c1Cl)N1CC2CNCC12

InChI Key InChIKey=LGTHYUQIIVQGDT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 38105   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM38105(US10093646, Example 20 | US10774065, Example 20 | ...)
Affinity DataIC50:  404nMpH: 7.2 T: 2°CAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM38105(US10093646, Example 20 | US10774065, Example 20 | ...)
Affinity DataIC50:  404nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM38105(US10093646, Example 20 | US10774065, Example 20 | ...)
Affinity DataIC50:  404nMMore data for this Ligand-Target Pair
In DepthDetails US Patent