BDBM381684 US10272079, Compound 41

SMILES CN(CCN(CC(O)=O)CC(=O)NCCOCCOCCNC(=O)NCCOCCOCCOCCN1CCN(CC1)c1cccc(c1)-c1nc(NC(N)=N)nc2ccc(Cl)cc12)CC(O)=O

InChI Key InChIKey=SFQHRWWTCDBRQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 381684   

TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM381684(US10272079, Compound 41)
Affinity DataIC50:  6.31nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM381684(US10272079, Compound 41)
Affinity DataIC50:  12.6nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent