BDBM381758 US10272079, Compound 115

SMILES CN(C)[C@H]1Cc2ccccc2[C@@H]1Oc1ccc(cc1)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)c1ccc(O[C@@H]2[C@H](Cc3ccccc23)N(C)C)cc1

InChI Key InChIKey=IVMBABOACDTTSP-SIAPTGDMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 381758   

TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM381758(US10272079, Compound 115)
Affinity DataIC50:  2.82nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

US Patent
LigandPNGBDBM381758(US10272079, Compound 115)
Affinity DataIC50: <1.00E+4nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent