BDBM383208 US10278929, Compound 4::US11337935, Compound 4

SMILES [NH3+]CCOCCOCCOc1c(Cl)cc(Nc2ccccc2C(O)=O)cc1Cl

InChI Key InChIKey=QEUUBUWXGRZBDK-UHFFFAOYSA-O

Data  1 Kd  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383208   

TargetTransthyretin(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM383208(US10278929, Compound 4 | US11337935, Compound 4)
Affinity DataKd:  285nMAssay Description:Dissociation Constants (Kd) associated with the binding of ligands to TTR are expressed in nM. Thermodynamic Binding Parameters associated with ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 383208   

CellTransthyretin(Homo sapiens (Human))
Leland Stanford Junior University

US Patent
SyringePNGBDBM383208(US10278929, Compound 4 | US11337935, Compound 4)
ITC DataΔG°: -8.93kcal/mole −TΔS°: -0.0712kcal/mole ΔH°: -8.86kcal/mole logk: 3.57E+6
pH: 7.5 T: 25.00°C 
Syringe InfoPC cidPC sid
In DepthDetails US Patent