BDBM38321 6-(3,4-dimethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::6-(3,4-dimethoxyphenyl)-3-(2-furyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::6-(3,4-dimethoxyphenyl)-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::MLS000037114::SMR000042111::cid_661498

SMILES COc1ccc(cc1OC)-c1nn2c(nnc2s1)-c1ccco1

InChI Key InChIKey=CDPQLJPWAPUNKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 38321   

TargetDiphosphomevalonate decarboxylase(Streptococcus pneumoniae D39)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM38321(6-(3,4-dimethoxyphenyl)-3-(2-furanyl)-[1,2,4]triaz...)
Affinity DataIC50:  2.35E+5nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM38321(6-(3,4-dimethoxyphenyl)-3-(2-furanyl)-[1,2,4]triaz...)
Affinity DataIC50:  19nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM38321(6-(3,4-dimethoxyphenyl)-3-(2-furanyl)-[1,2,4]triaz...)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibition of hexa-His-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) using AMC-labeled Arg-His-Lys-Lys(ac) as substrate asse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed