BDBM383345 9-(2-fluoro-4- methoxybenzyl)-6-methyl-4- (2-((1-methyl-1H-pyrazol-5- yl)amino)pyrimidin-4-yl)-8,9- dihydro-1,2,2a1,6- tetraazabenzo[cd]azulen- 7(6H)-one::US10278975, Compound I-85 R::US11376260, Example I-85S
SMILES COc1ccc(C[C@H]2CC(=O)N(C)c3cc(cc4nnc2n34)-c2ccnc(Nc3ccnn3C)n2)c(F)c1
InChI Key InChIKey=FOBHQXWBDGWDCB-KRWDZBQOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 383345
Affinity DataIC50: 25.9nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
Affinity DataIC50: <0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair