BDBM383456 N-(((5R,8S)-3-(2,6- difluorophenyl)-9,9-dimethyl- 5,6,7,8-tetrahydro-5,8- methanocinnolin-8-yl)methyl)-N- ethyl-4-methyloxazole-2- carboxamide::US10280144, Compound 172

SMILES CCN(C[C@@]12CC[C@@H](\C(=C\C(=N)c3c(F)cccc3F)C1=N)C2(C)C)C(=O)c1nc(C)co1

InChI Key InChIKey=UZFPVXXPVLMPFQ-XRYRGWSNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383456   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383456(N-(((5R,8S)-3-(2,6- difluorophenyl)-9,9-dimethyl- ...)
Affinity DataIC50:  7.90nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent