BDBM383544 2-[6-[1-(cyclopropylmethyl)piperidine-3-carbonyl]-2-methoxy-1-naphthyl]acetonitrile::US10280149, Example 53

SMILES COc1ccc2cc(ccc2c1CC#N)C(=O)C1CCCN(CC2CC2)C1

InChI Key InChIKey=SSSZOXBPBNLSFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383544   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383544(2-[6-[1-(cyclopropylmethyl)piperidine-3-carbonyl]-...)
Affinity DataIC50:  33.5nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent