BDBM383637 (1-cyclobutyl-4-phenylpiperidin-3-yl)(6-methoxynaphthalen-2-yl)methanone::US10280149, Example 141b

SMILES COc1ccc2cc(ccc2c1)C(=O)[C@H]1CN(CC[C@H]1c1ccccc1)C1CCC1

InChI Key InChIKey=SPGZZQKGUHJWCY-UIOOFZCWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383637   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383637((1-cyclobutyl-4-phenylpiperidin-3-yl)(6-methoxynap...)
Affinity DataIC50:  98.7nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent