BDBM383644 (1-cyclobutyl-4-isobutylpiperidin-3-yl)(6-methoxynaphthalen-2-yl)methanone::US10280149, Example 144a

SMILES COc1ccc2cc(ccc2c1)C(=O)[C@@H]1CN(CC[C@@H]1CC(C)C)C1CCC1

InChI Key InChIKey=AOWGSMLSSRLGTA-HYBUGGRVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383644   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383644((1-cyclobutyl-4-isobutylpiperidin-3-yl)(6-methoxyn...)
Affinity DataIC50:  5.60nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent