BDBM383688 2-(6-(1-cyclobutylpiperidine-3-carbonyl)-2-methoxynaphthalen-1-yl)acetonitrile::US10280149, Example 179a

SMILES COc1ccc2cc(ccc2c1CC#N)C(=O)[C@H]1CCCN(C1)C1CCC1

InChI Key InChIKey=FYBQNEKPUGASSS-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383688   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM383688(2-(6-(1-cyclobutylpiperidine-3-carbonyl)-2-methoxy...)
Affinity DataIC50:  5.65nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent