BDBM384577 4-({trans-4-[(2R or 2S)- 2- (hydroxymethyl)morpholin- 4- yl]cyclohexyl}amino) quinazoline-6-carbonitrile::US9932350, 3-11::US9932350, 3-12

SMILES OCC1CN(CCO1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N

InChI Key InChIKey=CPKRTHAQXKEYOM-BDWYFLKXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 384577   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384577(4-({trans-4-[(2R or 2S)- 2- (hydroxymethyl)morphol...)
Affinity DataIC50:  6nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384577(4-({trans-4-[(2R or 2S)- 2- (hydroxymethyl)morphol...)
Affinity DataIC50:  7nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent