BDBM384590 4-({trans-4-[(4aS,7aS or 4aR,7aR)- hexahydrocyclopenta[b] [1,4]oxazin-4(4aH)- yl]cyclohexyl}amino) quinazoline-6-carbonitrile::US9932350, 3-24

SMILES N#Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOC4CCCC34)c2c1

InChI Key InChIKey=QEHIZFWPFNGHTJ-QHGDOQTNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384590   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384590(4-({trans-4-[(4aS,7aS or 4aR,7aR)- hexahydrocyclop...)
Affinity DataIC50:  11nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent