BDBM384598 4-({trans-4- [cyclopropyl(methyl) amino]cyclohexyl}amino) quinazoline-6-carbonitrile::US9932350, 3-32

SMILES CN(C1CC1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N

InChI Key InChIKey=CMEIFPOLODTDNL-SHTZXODSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384598   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384598(4-({trans-4- [cyclopropyl(methyl) amino]cyclohexyl...)
Affinity DataIC50:  15nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent