BDBM384630 4-{[trans-4-(4- acetylpiperazin-1- yl)cyclohexyl]amino} quinazoline-6-carbonitrile::US9932350, 6-2
SMILES CC(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N
InChI Key InChIKey=UDRVLWWCRZFRSU-IYARVYRRSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 384630
Affinity DataIC50: 11nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of 5 mM ATP by enzymatic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of IRAK4 (unknown origin) by cell based assayMore data for this Ligand-Target Pair