BDBM384635 4-({trans-4-[4-(2- fluoropropanoyl)piperazin- 1- yl]cyclohexyl}amino) quinazoline-6-carbonitrile::US9932350, 6-7
SMILES CC(F)C(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N
InChI Key InChIKey=VNDJZGVMTVQRRI-DNLFPKPLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384635
Affinity DataIC50: 14nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair