BDBM384642 4-[(trans-4-{4-[(2,2- difluorocyclopropyl) carbonyl]piperazin-1- yl}cyclohexyl)amino] quinazoline-6-carbonitrile::US9932350, 6-14
SMILES FC1(F)CC1C(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)C#N
InChI Key InChIKey=CJEQVRVSHJSDMS-JHNFVTJISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384642
Affinity DataIC50: 13nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair