BDBM384659 4-{[(1S,2S,4S or 1R,2R,4R)-4-(4- fluoropiperidin-1-yl)-2- methylcyclohexyl]amino} quinazoline-6- carbonitrile::US9932350, 8-2

SMILES CC1CC(CCC1Nc1ncnc2ccc(cc12)C#N)N1CCC(F)CC1

InChI Key InChIKey=OBAJVRWQLPUOHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384659   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384659(4-{[(1S,2S,4S or 1R,2R,4R)-4-(4- fluoropiperidin-1...)
Affinity DataIC50:  10nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent