BDBM385993 2-(1-(2,3-dihydro-1H-pyrrolo[2,3]pyrimidin-4-yl)piperazin-4-yl)-2-(4-(trifluoro-methyl)phenyl)ethanamine::US10287300, Compound A2

SMILES NCC(N1CCN(CC1)c1ncnc2NCCc12)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=GEKRHWYIFQTBAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 385993   

TargetProline-rich AKT1 substrate 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM385993(2-(1-(2,3-dihydro-1H-pyrrolo[2,3]pyrimidin-4-yl)pi...)
Affinity DataIC50:  62nMAssay Description:A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM385993(2-(1-(2,3-dihydro-1H-pyrrolo[2,3]pyrimidin-4-yl)pi...)
Affinity DataIC50:  62nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent