BDBM386033 4-(4-(1-(2-fluorophenyl)-2-(piperidin-1-yl)ethyl)piperazin-1-yl)-7,8-dihydropteridin-6(5H)-one::US10287300, Compound A38

SMILES Fc1ccccc1C(CN1CCCCC1)N1CCN(CC1)c1ncnc2NCC(=O)Nc12

InChI Key InChIKey=UIGMCRCCIQGIIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 386033   

TargetProline-rich AKT1 substrate 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM386033(4-(4-(1-(2-fluorophenyl)-2-(piperidin-1-yl)ethyl)p...)
Affinity DataIC50: >1.00E+3nMAssay Description:A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM386033(4-(4-(1-(2-fluorophenyl)-2-(piperidin-1-yl)ethyl)p...)
Affinity DataIC50: >1.00E+3nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent