BDBM386111 N-(cis-1-(2,2-dimethylpropanoyl)-2- (((cis-4- isopropylcyclohexyl)oxy)methyl)- piperidin-3-yl)methanesulfonamide::US10287305, Example 53::US10508083, Example 53::US11292766, Example 53

SMILES CC(C)[C@@H]1CC[C@@H](CC1)OC[C@H]1[C@H](CCCN1C(=O)C(C)(C)C)NS(C)(=O)=O

InChI Key InChIKey=RWRREBZZLXYOQC-RDGPPVDQSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 386111   

TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386111(N-(cis-1-(2,2-dimethylpropanoyl)-2- (((cis-4- isop...)
Affinity DataEC50:  980nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386111(N-(cis-1-(2,2-dimethylpropanoyl)-2- (((cis-4- isop...)
Affinity DataEC50:  980nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386111(N-(cis-1-(2,2-dimethylpropanoyl)-2- (((cis-4- isop...)
Affinity DataEC50:  980nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent