BDBM389150 3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-5- carbonitrile::US9949951, 14

SMILES O=C1CC(C(=O)N1)c1c[nH]c2ccc(cc12)C#N

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 389150   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389150(3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-5- carboni...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389150(3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-5- carboni...)
Affinity DataIC50:  1.20E+4nMAssay Description:The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent