BDBM389604 N,N-dimethyl-N'-(2-{(E)-2-[4- (methylsulfonyl)phenyl]vinyl}quinazolin- 4-yl)ethane-1,2-diamine::US9951029, 121
SMILES CN(C)CCNc1nc(\C=C\c2ccc(cc2)S(C)(=O)=O)nc2ccccc12
InChI Key InChIKey=AVJWGIXYWFOLIY-JLHYYAGUSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 389604
Affinity DataIC50: 326nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of FLT3 D835Y (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of wildtype FLT3 (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair