BDBM389613 N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]vinyl}quinazolin- 4-yl)-N,N-dimethylpropane-1,3- diamine::US9951029, 130
SMILES CN(C)CCCNc1nc(\C=C\c2ccc(cc2)S(C)(=O)=O)nc2ccc(Cl)cc12
InChI Key InChIKey=KRSFGGHKQWELHV-KPKJPENVSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 389613
Affinity DataIC50: 873nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of FLT3 D835Y (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP...More data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of wildtype FLT3 (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP...More data for this Ligand-Target Pair