BDBM39048 5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxadiazole::5-(2-chloro-4-methyl-phenyl)-3-phenyl-1,2,4-oxadiazole::5-(2-chloro-4-methylphenyl)-3-phenyl-1,2,4-oxadiazole::MLS000115426::SMR000092530::cid_2056784

SMILES Cc1ccc(-c2nc(no2)-c2ccccc2)c(Cl)c1

InChI Key InChIKey=VKXJIEMSZDBZKJ-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 39048   

TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Photinus pyralis luciferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Photinus pyralis luciferase by Easy lite assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Photinus pyralis luciferase by PK-Light assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 3.07E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 3.34E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 3.97E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM39048(5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxa...)
Affinity DataIC50: 4.71E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay