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Target
Luciferin 4-monooxygenase
Ligand
BDBM39048
Substrate
n/a
Meas. Tech.
ChEMBL_476208 (CHEMBL923739)
IC50
150±n/a nM
Citation
 Auld, DS; Southall, NT; Jadhav, A; Johnson, RL; Diller, DJ; Simeonov, A; Austin, CP; Inglese, J Characterization of chemical libraries for luciferase inhibitory activity. J Med Chem 51:2372-86 (2008) [PubMed]  Article 
Target
Name:
Luciferin 4-monooxygenase
Synonyms:
LUCI_PHOPY | Luciferase
Type:
PROTEIN
Mol. Mass.:
60747.46
Organism:
Photinus pyralis
Description:
ChEMBL_938513
Residue:
550
Sequence:
MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAKKGGKSKL
  
Inhibitor
Name:
BDBM39048
Synonyms:
5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxadiazole | 5-(2-chloro-4-methyl-phenyl)-3-phenyl-1,2,4-oxadiazole | 5-(2-chloro-4-methylphenyl)-3-phenyl-1,2,4-oxadiazole | MLS000115426 | SMR000092530 | cid_2056784
Type:
Small organic molecule
Emp. Form.:
C15H11ClN2O
Mol. Mass.:
270.714
SMILES:
Cc1ccc(-c2nc(no2)-c2ccccc2)c(Cl)c1
Structure:
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