BDBM390899 N-{4-(2,4-difluorophenoxy)-3-[2-(3-methoxyprop-1-yn-1-yl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl]phenyl}ethanesulfonamide::US9957263, Example 163

SMILES CCS(=O)(=O)Nc1ccc(Oc2c(F)cccc2F)c(c1)-c1cn(C)c(=O)c2[nH]c(cc12)C#CCOC

InChI Key InChIKey=YHDCUCHKFBIWJB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390899   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM390899(N-{4-(2,4-difluorophenoxy)-3-[2-(3-methoxyprop-1-y...)
Affinity DataKi:  0.605nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM390899(N-{4-(2,4-difluorophenoxy)-3-[2-(3-methoxyprop-1-y...)
Affinity DataKi:  1.64nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent