BDBM392567 N-((3-chloro-6-fluoro-1H-indol-5- yl)methyl)-1-((3-chloro-8- fluoroquinolin-6-yl)methyl)-3-cyano- 1H-pyrazole-4-carboxamide::US10301284, Example 53::US10781200, Example 53

SMILES Fc1cc2[nH]cc(Cl)c2cc1CNC(=O)c1cn(Cc2cc(F)c3ncc(Cl)cc3c2)nc1C#N

InChI Key InChIKey=OOXUSHJPYMHNBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392567   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392567(N-((3-chloro-6-fluoro-1H-indol-5- yl)methyl)-1-((3...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM392567(N-((3-chloro-6-fluoro-1H-indol-5- yl)methyl)-1-((3...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent