BDBM392798 5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-ethyl-7-fluoro-benzimidazol-5-yl)-3H-benzimidazole-4-carboxamide::US10301305, Example 227

SMILES CCn1cnc2cc(cc(F)c12)-c1cc(N(C)CCN(C)C)c(C(N)=O)c2[nH]cnc12

InChI Key InChIKey=VFQBWAQNYMCLQG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 392798   

TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
Mutabilis

US Patent
LigandPNGBDBM392798(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-ethyl...)
Affinity DataIC50:  32nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Streptococcus agalactiae serotype V (strain ATCC B...)
Mutabilis

US Patent
LigandPNGBDBM392798(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-ethyl...)
Affinity DataIC50:  1.30E+3nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecium E1679)
Mutabilis

US Patent
LigandPNGBDBM392798(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-ethyl...)
Affinity DataIC50:  83nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Mutabilis

US Patent
LigandPNGBDBM392798(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-ethyl...)
Affinity DataIC50:  30nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent