BDBM393426 N-(5-((2S,5R,6S)-5-amino-6- fluorooxepan-2-yl)-1-methyl- 1H-pyrazol-4-yl)-2-((R)-6,8- difluoro-4-hydroxychroman-7- yl)thiazole-4-carboxamide::US9963446, Example 112

SMILES Cn1ncc(NC(=O)c2csc(n2)-c2c(F)cc3[C@H](O)CCOc3c2F)c1[C@@H]1CC[C@@H](N)[C@H](F)CO1

InChI Key InChIKey=JUZOWLSJBBSRIU-KFZJALRRSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393426   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM393426(N-(5-((2S,5R,6S)-5-amino-6- fluorooxepan-2-yl)-1-m...)
Affinity DataKi:  0.00400nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent