BDBM393432 N-[5-[(2S,5R,6S)-5-amino-6- fluoro-oxepan-2-yl]-1-methyl- pyrazol-4-yl]-2-(5-methoxy-3- methyl-2-pyridyl)thiazole-4- carboxamide::US9963446, Example 119

SMILES COc1cnc(-c2nc(cs2)C(=O)Nc2cnn(C)c2[C@@H]2CC[C@@H](N)[C@H](F)CO2)c(C)c1

InChI Key InChIKey=WVIFKINRRYYQMF-CPUCHLNUSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393432   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

US Patent
LigandPNGBDBM393432(N-[5-[(2S,5R,6S)-5-amino-6- fluoro-oxepan-2-yl]-1-...)
Affinity DataKi:  0.0430nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent