BDBM393536 US9969687, Compound 201
SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(Cl)c2C(=O)N(Cc3ccncc3)C(=O)c12
InChI Key InChIKey=IOOYJLRHHNGMEA-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 393536
Affinity DataKi: 8nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intrace...More data for this Ligand-Target Pair
Affinity DataKi: >100nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCl25-mediated cell migration preincubated for 30 mins followed C...More data for this Ligand-Target Pair