BDBM394182 US9975876, 4::methyl 2-{[(3R,6R)-1-{[4-fluoro-2- (2H-1,2,3-triazol-2- yl)phenyl]carbonyl}-6- methylpiperidin-3-yl]oxy}-4- methoxypyridine-3-carboxylate

SMILES COC(=O)c1c(OC)ccnc1O[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccc(F)cc1-n1nccn1

InChI Key InChIKey=YTEOVDFIBCSYSS-GDBMZVCRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394182   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394182(US9975876, 4 | methyl 2-{[(3R,6R)-1-{[4-fluoro-2- ...)
Affinity DataIC50:  3.20E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394182(US9975876, 4 | methyl 2-{[(3R,6R)-1-{[4-fluoro-2- ...)
Affinity DataIC50:  764nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent