BDBM395712 4-amino-N-((1S,3R)-3-(5-cyano-4-(1H-indol-3-yl)pyrimidin-2-ylamino)cyclohexyl)benzamide::US10308648, Compound 107::US10865206, Compound 107

SMILES Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(C#N)c(n1)-c1c[nH]c2ccccc12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395712   

TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395712(4-amino-N-((1S,3R)-3-(5-cyano-4-(1H-indol-3-yl)pyr...)
Affinity DataIC50: <100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies(Grand Island, N.Y.) using their commercially available AdaptaŽ kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395712(4-amino-N-((1S,3R)-3-(5-cyano-4-(1H-indol-3-yl)pyr...)
Affinity DataIC50: <100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent