BDBM397965 US10604536, Compound 37::US9994590, Compound 37
SMILES COc1cc(OC)c2nc(C3CC3c3nc4c(C)ncc(C)n4n3)c(C)n2c1
InChI Key InChIKey=TZDBYKHXAFMGHE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 397965
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharamaceuticals
US Patent
Sunovion Pharamaceuticals
US Patent
Affinity DataIC50: 55nMAssay Description:The compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 enzyme expressed in...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharamaceuticals
US Patent
Sunovion Pharamaceuticals
US Patent
Affinity DataIC50: 55nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair