BDBM397965 US10604536, Compound 37::US9994590, Compound 37

SMILES COc1cc(OC)c2nc(C3CC3c3nc4c(C)ncc(C)n4n3)c(C)n2c1

InChI Key InChIKey=TZDBYKHXAFMGHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397965   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharamaceuticals

US Patent
LigandPNGBDBM397965(US10604536, Compound 37 | US9994590, Compound 37)
Affinity DataIC50:  55nMAssay Description:The compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 enzyme expressed in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharamaceuticals

US Patent
LigandPNGBDBM397965(US10604536, Compound 37 | US9994590, Compound 37)
Affinity DataIC50:  55nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent