BDBM397998 2-((R)-3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)-4-methyl-4-(piperazin-1-yl)pent-2-enenitrile::US11040980, Example 6::US9994576, 6

SMILES CC(C)(C=C(C#N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12)N1CCNCC1

InChI Key InChIKey=HGXITWGZZVLXPJ-HSZRJFAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397998   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM397998(2-((R)-3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-...)
Affinity DataIC50:  0.400nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM397998(2-((R)-3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-...)
Affinity DataIC50:  0.400nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent