BDBM401009 US10005735, Compound 18
SMILES FC(F)(F)c1ccc(CNC(=O)c2cnc3c(S)cccc3c2)cc1
InChI Key InChIKey=HCWIACCIZLIHBR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 401009
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
California Institute of Technology
US Patent
California Institute of Technology
US Patent
Affinity DataIC50: 700nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
California Institute of Technology
US Patent
California Institute of Technology
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair