BDBM402215 (9aS)-2-(5-benzyloxypyrazin- 2-yl)-7-[2,6-difluoro-4-(2- phenylethynyl)phenyl]-9a- methyl-4,9-dihydro-3H- pyrazino[1,2-c]pyrimidine- 1,6,8-trione::US10011607, 45

SMILES C[C@@]12CC(=O)N(C(=O)N1CCN(C2=O)c1cnc(OCc2ccccc2)cn1)c1c(F)cc(cc1F)C#Cc1ccccc1

InChI Key InChIKey=UJFCEGZDJCUBRY-XIFFEERXSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402215   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM402215((9aS)-2-(5-benzyloxypyrazin- 2-yl)-7-[2,6-difluoro...)
Affinity DataEC50:  190nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent