BDBM404211 (2S,5R)-5-(2-cyanophenyl)-1-(2'-methoxy-[1,1'-biphenyl]-4-carbonyl)pyrrolidine-2-carboxylic acid::US10017468, Compound 386::US10781171, Compound 376

SMILES OC(=O)[C@@H]1CC[C@@H](N1C(=O)C1CCN(CC1)c1ccc(cc1[N+]([O-])=O)C(F)(F)F)c1ccccc1Cl

InChI Key InChIKey=AGQCXWGBBORZCD-QUCCMNQESA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404211   

TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM404211((2S,5R)-5-(2-cyanophenyl)-1-(2'-methoxy-[1,1'-biph...)
Affinity DataKi: <1.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Epics Therapeutics

US Patent
LigandPNGBDBM404211((2S,5R)-5-(2-cyanophenyl)-1-(2'-methoxy-[1,1'-biph...)
Affinity DataEC50:  600nMAssay Description:The following assay can be used for determination of GPR43 activation. When a GPCR is in its active state, either as a result of ligand binding or co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent