BDBM404321 (1-Cyclopropyl-1-{5-[(3R,6R)-6-methyl-1-{[2-(2H-1,2,3-triazol-2-yl)phenyl]carbonyl}piperidin-3-yl]isoxazol-3-yl}ethanol) (Ex. 52) and (1-Cyclopropyl-1-{5-[(3R,6R)-6-methyl-1-{[2-(2H-1,2,3-triazol-2-yl)phenyl]carbonyl}piperidin-3-yl]isoxazol-3-yl}ethanol) (Ex. 53)::US10017504, 52
SMILES CON(C)C(=O)c1cc(on1)[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccccc1-n1nccn1
InChI Key InChIKey=MIBXPEQHKVZDQE-HUUCEWRRSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 404321
Affinity DataIC50: 2.36E+3nMAssay Description:n a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with the...More data for this Ligand-Target Pair
Affinity DataIC50: 47.3nMAssay Description:n a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with the...More data for this Ligand-Target Pair