BDBM404328 (2-{3-[(3R,6R)-6-Methyl-1-{[2-(2H-1,2,3-triazol-2-yl)thiophen-3-yl]carbonyl}piperidin-3-yl]isothiazol-5-yl}propan-2-ol)::US10017504, 59

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccsc1-n1nccn1)c1cc(sn1)C(C)(C)O

InChI Key InChIKey=CLZSKYPWRDGDGO-CHWSQXEVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404328   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM404328((2-{3-[(3R,6R)-6-Methyl-1-{[2-(2H-1,2,3-triazol-2-...)
Affinity DataIC50:  3.96E+3nMAssay Description:n a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM404328((2-{3-[(3R,6R)-6-Methyl-1-{[2-(2H-1,2,3-triazol-2-...)
Affinity DataIC50:  24.9nMAssay Description:n a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent